NFL Best Bets and Picks for the 49ers vs. Rams NFC Championship Game

For the third time this season, a pair of NFC West Division rivals are set to face off on Sunday night. This trilogy matchup between the San Francisco 49ers and Los Angeles Rams will certainly carry heightened stakes. The winner of the NFC Championship Game will book their spot in Super Bowl LVI. What more do you need to seek out some winning NFL best bets for this game?

With help from OddsShopper, the following article highlights three NFL best bets and picks for the NFC Championship Game showdown between the 49ers and Rams.

Best NFL Bets and Picks | NFC Championship Game

With OddsShopper, finding the best NFL picks is fast and simple. All users have to do is filter the prop selections, sort the page and find the best pick to bet. The process is extremely quick and highly effective. Try out the tool for yourself tonight with the three featured NFL best bets below!

Also be sure to check out OddsShopper’s matchups page, breaking down all the data for each game on a given slate.

Kyle Juszczyk Over 8.5 Receiving Yards (-115, DraftKings) 

Fullback is largely a dying position in the modern-day NFL. Among the few pure players that are left, none offer a more versatile skill set at the position than Kyle Juszczyk. The first layer to this prop bet is the general belief that the 49ers will need to be successful in the passing game if they are to have a shot in Sunday’s NFC Championship Game. The Rams will undoubtedly stack the box against the run and force Jimmy Garoppolo to beat them through the air. He already did this once back in Week 18, and the 49ers figure to have a plan of their own in place. 

While Juszczyk is clearly not the most explosive playmaker in this offense, he is often left in to help block on passing downs. As a result, he actually serves as a reliable check-down option for Garoppolo. Prior to last week’s obscure game, Juszczyk had seen multiple targets in seven of the last eight games. Only four times all season has he seen fewer than two total targets in a game. The fact that OddsShopper shows one sportsbook listing this prop a full yard higher at 9.5 is very telling about where the NFL betting market is leaning. Awesemo’s projection of 19.19 yards leads to a massive expected ROI value of 73% when bet at the best price of -115.


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Rams Team Total Under 20.5 Points (-120, BetMGM)

After getting destroyed and only scoring 10 points in the first meeting against the 49ers this season, the Rams totaled 24 in their Week 18 overtime loss. While this is a rather daring play given that Los Angeles is the NFL betting favorite for Sunday’s matchup, the plus-money price certainly adds to the appeal.

Defensively, the 49ers ranked second in adjusted efficiency against the run this season. San Francisco has one of the best defensive fronts in the NFL. The line is highlighted by pass-rusher Nick Bosa and tackle Arik Armstead while Fred Warner is perhaps the best linebacker in the game today. Against a vulnerable Rams offensive front that is made worse by Sean McVay’s poor blocking schemes, the 49ers could conceivably have a field day. They certainly did so in the Week 18 matchup, sacking Stafford five times. Of course, the 49ers will also be trying to play a run-heavy, ball-control game on offense as well. 

With OddsShopper showing that the over/under for the game set at either 45.5 across the majority of the NFL betting market, a 24-21 or 24-20 final score is certainly considered to be within the realm of realistic possibilities according to oddsmakers and the betting market. For what it’s worth, the total has gone over in five of the Rams’ last seven home games when playing as the betting favorite. While bettors should never bet solely based on a trend, it is certainly interesting to note and consider.

Matthew Stafford Over 0.5 Interceptions (-115, BetMGM)

The 49ers’ defense has only come up with nine total interceptions this entire NFL season. Only four teams had fewer INTs than San Francisco. Oddly enough, four of those nine interceptions were thrown by Matthew Stafford. Stafford threw two picks in each of the regular-season matchups against the 49ers. Considering that he threw 17 total interceptions this season, just under 25% of Stafford’s picks came against San Francisco. In reality, his performance across the board against teams that primarily play zone coverage was much worse than against man.

With the most vulnerable part of the 49ers’ defense being the secondary, they are forced to play zone coverage out of necessity when matched up against star pass-catchers like the ones Los Angeles has. Thus, it seems reasonable to anticipate that the Rams will air it out early and often in the NFC Championship Game. We saw Stafford succumb to multiple picks when trailing and when playing with a double-digit lead against the 49ers this season. For as talented of a quarterback as he is, there are bound to be some nerves that come with playing for a spot in the Super Bowl for the first time in his career. Look for Stafford to have at least one INT in Sunday’s game.

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