Are you trying to build the perfect DraftKings MLB DFS lineup tonight? With 12 games on the slate and plenty of volatility in the pitching pool, it’s a high-leverage spot to find an edge. Josh and Loughy are breaking down the best plays, top stacks and smart pivots — all using data from Stokastic’s advanced MLB Sims tools.
Perfect DraftKings MLB DFS Lineup: Optimal Strategy
Top Pitchers for Your MLB DFS Lineup
Robbie Ray (SEA) – $10,200
If you’re looking for a high-floor, high-ceiling ace, Ray is your guy. With a 28% strikeout rate and elite home splits, he leads all pitchers in Top 2 Pitcher Probability for tonight. The Guardians are bottom 5 in ISO and strike out at a 23% clip agaomst lefties. It’s a premium spot in one of the league’s best pitcher parks.
Will Warren (NYY) – $7,500
For optimizing value in your lineup, Warren stands out. He’s the highest-projected mid-tier pitcher by strikeout rate (28%) and faces an Angels offense that whiffs often and lacks plate discipline. As a -260 favorite at home, he fits any DraftKings MLB DFS build.
Pitcher Pivots for GPPs
Want to avoid the chalk and make your DraftKings MLB DFS lineup unique?
- Bryan Woo (SEA) – Facing a Rafael Devers-less Boston team at home.
- Andrew Abbott (CIN) – Low ownership, decent strikeout upside against the Twins.
- Ben Brown (CHC) – Cheap and volatile but high strikeout potential against Milwaukee.
- Walker Buehler (BOS) – Just $7,000, viable low-owned flier in pitcher-friendly conditions.
Top DraftKings MLB DFS Stack: Houston Astros
For the perfect DraftKings lineup, the Houston Astros should be your core stack.
- Matchup: JP Sears has allowed a .215 xISO and sub-20% strikeout rate to righties since 2023 — a dream for Houston’s power bats.
- Ballpark Upgrade: George Steinbrenner Field ranks among the best for righty power (123 park factor this year).
- Top Stack Score: Houston leads the entire slate in both Top Stack Probability and Value Score.
Target Bats
- Jeremy Peña (SS) – Strong value, power upside.
- Jose Altuve (2B) – Smashes lefties.
- Yainer Diaz (C) – Pop and positional scarcity.
- Cam Smith (OF) – Salary saver with upside.
- Optional Add-On: Christian Walker (1B)
Simulation Results
Final Word: Dominate MLB DFS Tonight
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