MLB DFS Picks, Spotlight Pitchers & Top Stacks: Baltimore Early and Arizona Late! (May 17)

DraftKings NFL Best Ball Promo

Saturday brings a few different afternoon lock times, with the featured action taking the shape of an 8-game set with a 7:05 p.m. ET first pitch on DraftKings, FanDuel and Yahoo. Today we’re breaking down MLB DFS picks using Stokastic’s industry-leading tools and MLB DFS projections to learn how to build MLB DFS stacks, find the top pitchers and craft optimal daily fantasy baseball lineups. Matthew Boyd is the key arm for the early action, while Zac Gallen gets the honors for the featured-slate. The Stokastic MLB DFS Top Stacks Tool is recommending the Diamondbacks at home in Arizona with the Chase Field roof open and RHP German Marquez on the mound, while it is the Batters of Birdland against RHP Jake Irvin for the early tournaments.

MLB DFS Picks: Spotlight Pitchers and Top Stacks | May 17

If you’re ready to take your DFS game to the next level, a Stokastic+ subscription is exactly what you need. Our Sims and data have helped countless users make a ton of money on DraftKings, FanDuel and beyond. If you want to join them, try it out today and start taking down MLB DFS slates!


MLB DFS Picks: Spotlight Pitchers

Main Slate Primary Pitching Target: RHP Zac Gallen (ARI vs. COL)

Diamondbacks vs. Rockies – 3.3 implied runs
First Pitch: 8:10 p.m. ET
$9,000 at DraftKings
$10,200 at FanDuel
$47 at Yahoo

The Stokastic MLB DFS Top Pitchers tool is going back to Arizona tonight, against an offensive Colorado offense. Last night RHP Corbin Burnes worked six-scoreless innings, with 10 strikeouts, as the Rockies were also blanked by the three relievers after him.

This Stokastic user just bagged $40K on DraftKings using Stokastic’s tools! Check out this breakdown of zokin’s lineup entries, and sign up for Stokastic+ MLB to join them.

Tonight RHP Zac Gallen is on the mound and while he has scuffled this season, he should make good in this get right spot. The Chase Field roof will be open and the game has a 5:10 p.m. local start. This should boost the offense for both teams, though the Rockies are “improving” from one of the worst offenses in the league against right-handed pitching to “merely” well-below average.

Part of the struggles for Gallen have been in a tough schedule, with games two games against the Cubs, as well as facing the Dodgers, Yankees and Braves. To his credit, he held the Mets to just two runs in 13 innings this month, so going against Colorado should feel like a walk in the park.

Colorado has a 67 wRC+ against right-handed hurlers. Weighted runs created plus is an advanced metric that neutralizes different variables such as park factors, creating a league-wide scoring efficiency baseline of 100.

This advanced metric indicates that the Rockies create runs 33% less efficiently than league average and are well behind the 76 wRC+ of the White Sox, which are the second-most pathetic team in the league.

The projected lineup for the Rockies has a 28.6% strikeout rate against right-handed pitchers over the last season and change. Nick Martini (18.7%) is the only batter who is below 24%, which is crazy. The team also has a substandard 6.5% walk rate and while the .166 ISO is solid, it also includes their Coors Field production.

Early Slate Primary Pitching Target: LHP Matthew Boyd (CHC vs. CHW)

Cubs vs. White Sox – 4.1 implied runs
First Pitch: 2:20 p.m. ET
$9,300 at DraftKings
$10,600 at FanDuel
$46 at Yahoo

In an interesting twist, I found LHP Matthew Boyd on waivers in two of my competitive daily leagues this morning, which was a bonus when seeing the ace-treatment he is getting by the various salary algorithms for his matchup this afternoon against the hapless White Sox offense.

The 34-year-old has been healthy this season, ranking in the top-20 with his 2.78 ERA, despite facing the Dodgers and Padres twice each along with road games against the Mets and Diamondbacks. Only Los Angeles put up more than three runs against him, though only half of the six the boys in blue plated were earned.

Take the easy gift and then on DraftKings close your eyes and choose between RHPs Drew Rassmussen in Miami versus the Marlins and Reese Olson in Toronto against the Blue Jays.

MLB DFS Picks: Top Stacks

Main Slate Primary Target: Arizona Diamondbacks

Diamondbacks vs. Rockies – 6.1 implied runs
First Pitch: 8:10 p.m. ET
Opposing Starter: RHP German Marquez
DK Top Stack %: 14.6%
FD Top Stack %: 14.7%

The Stokastic MLB DFS Top Stacks Tool is running back the recommendation against RHP German Marquez, after he had his start pushed back by one day. The Arizona team total is down half a run from yesterday’s preliminary assessment. The team plated five runs in four innings against rookie LHP Carson Palmquist, on the way to an 8-0 victory.

Marquez has been healthy for only 20 innings in 2023, four in 2024 and 37 this year. His strikeouts per nine innings have fallen all the way down to 4.86 this year after the Colorado ace averaged 9.34 per nine in 532 innings between 2017 and 2019. In five road appearances this season, Marquez has faced just 96 batters, ceding a triple-slash line of .356/.404/.433, suffering 24 runs with a scant 14 strikeouts.

The Chase Field roof is scheduled to be open tonight, which is helping to boost the Arizona team total to a lofty 6.1 runs. Corbin Carroll and Ketel Marte have hefty salaries on DraftKings at $6,000 and $5,300, respectively. However, no other batsmen are going to bust budgets, though with all of the aces on the mound tonight taking up cap space, gamers may not get to the top of the order. That is something to pay attention to as spending on this duo could be a way to create in-stack differentiation, depending on how the field approaches this conundrum.

FanDuel whiffed on the salaries for Josh Naylor ($3,000), Lourdes Gurriel ($2,900) and Pavin Smith ($2,900), so even though Carroll ($4,500) and Marte ($3,700) have higher-than-normal salaries for the blue site, stacking the team is not an issue. In addition to the previous five hitters, Eugenio Suarez rounds out the six most desirable bats. There is no need to gush about how this collective crew is showing fields of green on the hitting dashboards as the team total and projections are already flagging them as the most likely top stack for Saturday. Jordan Lawlar is just $2,400 on DraftKings and he is the discount dandy of the night, from the nine-hole.

The Dodgers look good at home against LHP Tyler Anderson, though we need to keep in mind that Anderson usually does a good job of limiting opposing offenses from mega-scores. In eight starts this season, he has yet to cede more than three runs in a game, though he does have a pair of multi-home run efforts. Last year he allowed more than four runs only twice, though he had five multi-home run games in his 31 appearances. Gamers are probably remembering 2023, when the 35-year-old had eight games of more than five earned runs in his 27 outings, with four multi-home run affairs.

Early Slate Secondary Target: Baltimore Orioles

Orioles vs. Nationals – 4.8 implied runs
First Pitch: 7:40 p.m. ET
Opposing Starter: RHP Jake Irvin
DK Top Stack %: 14.4%
FD Top Stack %: 14.2%

The Cubs and White Sox are squaring off at Wrigley Field this afternoon, with the Cubbies a team that can make RHP Sean Burke pay for his inordinate amount of walks, with 11 in his last 16.1 innings resulting in only two earned runs. He has only nine strikeouts in these appearances against Miami and in Kansas City, so the bill is about to come due.

The Tampa Rays and Marlins are facing off in Miami, with struggling RHP Sandy Alcantara toeing the rubber for the home team. Josh Lowe just returned to the lineup, which provides another steady presence among rookies like Kameron Misner and Chandler Simpson. The 2023 National League Cy Young Award winner has been throwing batting practice this season and Tampa has enough power and discipline to post strong numbers.

That brings us to the Batters of Birdland, who are hosting the Washington Nationals in the Battle of the Beltway this weekend. The Nats will be sending out RHP Jake Irving against Baltimore, with the third-year starter getting by on smoke-and-mirrors. In his last three games, spanning 17.1 innings, the 28-year-old has allowed eight walks, five home runs and managed only three strikeouts. Yes, three as in the number after one and two.

The O’s have won only two of their last 12 games, topping three runs only twice. This lineup is just too talented to continue to slump en masse. On FanDuel, only two projected starters are more than $2,900, though things are a little more realistic on DraftKings for Gunnar Henderson ($5,200), Adley Rutschman ($4,500), Ryan O’Hearn ($4,600) and Cedric Mullins ($4,700). Still Jackson Holiday ($3,700) and Ryan Mountcastle ($3,600) should be near the top of the order, averaging down the overall cap hit for the full-stack.

Today’s Top Sports Betting Picks

If you’re serious about making sharp MLB DFS picks, you already know that long-term success starts with using the right tools. The same approach applies to sports betting — and that’s where Portfolio EV shines.

Take Griffin Canning under 4.5 strikeouts, for example. This is a +EV bet, meaning it has positive expected value based on the best odds available. But smart betting with Portfolio EV isn’t about chasing isolated plays; it’s about consistently firing off a high volume of +EV wagers. With the Mass Entry tool, you can scale your action and let the math compound your edge over time.

Just like one DFS lineup won’t guarantee a takedown, one bet won’t define your night — it’s the consistent process that leads to profit.

Looking for NBA best bets? Look no further - we've got a couple of +EV bets that are backed by NBA DFS Projections and Portfolio EV.
Wondering what is Portfolio EV? Well, it’s the best sports betting tool on the market, and you can get it FREE! Check it out now and start building your bankroll.

Portfolio EV is built for bettors who want to win over the long haul. By identifying market inefficiencies, the best available odds and stacking a portfolio of +EV bets, it sets you up for compounding returns over time. This isn’t about chasing hot streaks — it’s about trusting the numbers and executing a smart, consistent and scalable strategy to beat the books.

Canning is in the midst of a career-year in his first season for the New York Mets. Tonight he is facing the Yankees in this cross-town rivalry, living on borrowed time. The 29-year-old is a middle of the rotation starter on his best days, so his 2.36 ERA is a bit of a surprise through 42 innings, when considering his elevated 3.43 walks per nine innings and a career 1.52 home runs per nine.

This year he has an 0.86 home runs per nine innings rate, which is likely to course correct at some point. The Projected lineup for the Bronx Bombers has a 23.4% strikeout rate against right-handed pitching over the last season-plus, with Canning posting an 18.8% rate in the same timeframe. Expect some extra-base hits from Aaron Judge, Ben Rice, Cody Bellinger, Austin Wells and Trent Grisham being the likely producers, which could lead to a short afternoon for Canning.

How to get the most out of your MLB DFS picks with Stokastic Sims!

Eric "EMac" MacPherson won the 2007 Fantasy Baseball grand prize (trip for two to the MLB All-Star game) in the Roto format on ESPN. He won again in 2008, this time in the H2H format. As one of the early adopters of daily fantasy sports, EMac has been providing content for baseball and basketball as well as both professional and college football since 2012 for a variety of websites including DraftKings Playbook, FanVice, RotoWorld, Daily Fantasy Bootcamp, and RotoGrinders. He is well into his third decade of fantasy sports and has a wealth of knowledge and experience. Follow him on Twitter @EMacDFS or contact EMac by emailing [email protected].

Related Articles

DFS Winners from the Stokastic Community

Subscribe to the Stokastic newsletter

DFS advice, exciting promos, and the best bets straight to your inbox

Stokastic.com - Daily Fantasy Sports and Sports Betting Data, Tools, & Analytics

Please play responsibly. Only customers 21 and over are permitted to play. If you or someone you know has a gambling problem and wants help, call 1-800-GAMBLER.