MLB DFS Picks, Spotlight Pitchers & Top Stacks: Happy Nathan Eovaldi Day! (Aug. 22)

Friday winds down the work week with a tantalizing 13-game featured slate on DraftKings and FanDuel, with a 7:05 p.m. ET first pitch. Yahoo is including all 30 teams in their player pool, with a 6:40 p.m. E.T lock time.. The MLB DFS picks today are loaded with value … if you have the right tools. Stokastic’s MLB DFS Sims optimizer and MLB DFS projections highlight the top stacks, best arms and high-upside one-offs to anchor your lineups.

MLB DFS Optimizer Picks Today: Spotlight Pitchers & Stacks

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MLB DFS Optimizer Picks Today: Spotlight Pitchers

Main Slate Primary Pitching Target: RHP Nathan Eovaldi (TEX vs. CLE)

Rangers vs. Guardians – 3.4 implied runs
First Pitch: 8:05 p.m. ET
$10,300 at DraftKings
$10,500
at FanDuel
$50 at Yahoo

The Stokastic MLB DFS Top Pitchers tool sees a variety of targets tonight, with RHPs Nathan Eovaldi and Bryan Woo as the co-leaders. Ultimately it is Eovaldi who earned the top billing for this section, though it is a close call and before first pitch, there is no wrong answer.

Both pitchers are at home, which gives the advantage to Woo, since T-Mobile Park is consistently the most pitching-friendly venue in the league. The roof is likely to be closed at Globe Life Field in Arlington, which also helps hurlers. Woo has been the most efficient starter in the league, averaging 14.38 pitches per inning. He is tied for the league lead with 18 quality starts and he has closed out the sixth inning in all 24 of his appearances.

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There are some strikeouts available in the A’s lineup, with four hitters striking out at a 24.5% or higher rate against righties this season. Of course the tradeoff is running a power gauntlet of brawny bats, including lefties Nick Kurtz (.394 ISO, 255 plate appearances), Tyler Soderstrom (.239 ISO, 399 PAs) and Lawrence Butler (.181 ISO, 408 PAs).

Eovaldi will be battling against one of the most complete bats in the game, with switch-hitting maestro Jose Ramirez holding down the middle of the Cleveland lineup, though the back of the order has plenty of strikeout upside, with a lack of power in Gabriel Arias, Angel Martinez and Brayan Rocchio. Catcher Bo Naylor and prospect CJ Kayfus have pop, though they also look like wind machines at the plate, getting lots of air when they do not make contact.

Let personal preference be your guide when deciding between these aces, with both being a strong pairing for DraftKings “cash games” (H2Hs, 50/50s, 3-mans, etc.).

Main Slate Value Target: RHP Zebby Matthews (MIN vs. CHW)

Twins at White Sox – 4.1 implied runs
First Pitch: 7:40 p.m. ET
$7,700 at DraftKings
$8,300
at FanDuel
$41 at Yahoo

It will be interesting to see how popular RHP Zebby Matthews ends up projecting for the featured tournaments on DraftKings. Strikeout potential is the main thing that sets the 25-year-old above the other discount dandies.

Across ten starts this season and nine last year, Matthews has struck out nearly one batter per inning, increasing his strikeout rate from 24.3% last year to a robust 29.9% in 2025. The White Sox have been pesky of late, though the youth and inexperience up and down the lineup card tends to create inconsistent results between the lines.

There are no longer any easy outs in the Chicago lineup, which has a nice mix of youngsters and veteran journeymen. However, there also are no terrifying hitters. Matthews has allowed four round-trippers in his last two starts, though he gets a bit of a mulligan as a trio of taters occurred in Yankee Stadium. On the positive side of the ledger, he has a hefty 21 strikeouts in his last 14.2 innings, with matchups home and away against Detroit on either side of the New York visit.

For those not enthralled with Matthews, veteran LHP Jose Quintana is in Milwaukee, taking on the San Francisco Giants. The well-travelled Quintana does not have anything close to the strikeout potential of Matthews, but he has experience and savvy, which should position him for a chance at the win bonus and a quality start.

MLB DFS Optimizer Picks Today: Top Stacks

Main Slate Target: Tampa Bay Rays

Rays vs. Cardinals – 4.5 implied runs
First Pitch: 7:35 p.m. ET
Opposing Starter: RHP Miles Mikolas
DK Top Stack %: 5.3%
FD Top Stack %: 5.1%

The Stokastic MLB DFS Top Stacks Tool again likes both sides of the Steinbrenner Field festivities. These teams played yesterday, combining for 11 runs and the weather is again favorable for offenses, with temperatures in the mid-80s, with elevated humidity. There could be sporadic rain, though nothing is expected to be serious enough to cause more than a delay.

In a scheduling twist, these teams get Saturday off, with the game having been moved to Thursday in order to accommodate the Tampa Bay Buccaneers vs. Buffalo Bills preseason game, taking place in the same complex. That does not have any impact on today’s action, but it is an advanced note as to why the teams are off tomorrow.

Over his last two outings, RHP Miles Mikolas has managed to avoid home runs, though he does have six walks in these 11.2 innings, against only four strikeouts. The Lizard King will do his best to absorb innings, but the cost is likely to be extracted by the Tampa offense in the form of multiple runs. Since the start of July, Mikolas has made nine starts, with a 6.15 ERA, 6.58 FIP and 4.87 xFIP across 45.1 frames. In this stretch he has also suffered 14 home runs and 24 total extra base hits, with only 24 strikeouts.

Look to Brandon Lowe and Junior Caminero as a strong lefty-righty combo, as the foundation for any Tampa stack as well as a duo or one-offs in all formats. Catcher Hunter Feduccia is a screaming value on DraftKings ($2,200) and Yahoo ($9), fulfilling the pesky backstop requirement.

St. Louis collectively is not particularly effective at preventing steals, which bodes well for rookie Chandler Simpson, who is second in the league this season with 36 steals, only four behind former teammate Jose Caballero, despite not being called up to The Show until mid-April and also spending three weeks in June with Triple-A Durham, to work on his skills in the batter’s box.

Lowe, Caminero and Simpson have all cracked the $5,000 salary level on DraftKings, though in addition to Fedducia, switch-hitting rookie Jake Mangum is also cheap and first baseman Bob Seymour is likely to get the start, with Yandy Diaz suffering an injury on Thursday. Seymour had 28 home runs at various levels in the minors last year and he had 30 at Triple-A Durham, prior to his mid-August callup.

Turning our attention to the Cardinals, they will be facing RHP Adrian Houser, who has made three road starts for the Rays, with tonight being his first at Steinbrenner Field. In that trio of tilts, Houser has been very mediocre, with a 5.17 ERA, 4.65 FIP and 4.63 xFIP. These appearances were in San Francisco, Seattle and Anaheim, which are three of the more pitching friendly parks in the league.

Lefty power has long been an issue for Houser, regardless of his uniform, so prioritize Lars Nootbaar, Alec Burleson and Nolan Gorman. This trio will be spread out across the top-six hitters, so catcher Willson Contreras and shortstop Masyn Winn are options to create a more synergistic stack, by filling the gaps.


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Late Slate Contrarian Target: Los Angeles Dodgers

Dodgers at Padres – 4.7 implied runs
First Pitch: 9:40 p.m. ET
Opposing Starter: RHP Yu Darvish
DK Top Stack %: 1.4%
FD Top Stack %: 1.7%

Tonight the Dodgers are in San Diego, facing old friend and foe RHP Yu Darvish. The venerable veteran celebrated his 39th birthday last week and while he is a clear Hall of Famer, this has been a rough season. Elbow inflammation delayed his MLB debut until early-July and he has yet to find his footing.

This will be the second-consecutive start against Los Angeles, with the Dodgers getting to Darvis for a pair of longballs and four runs, in four innings. To his credit, the five-time All-Star has been challenging hitters, getting 34 strikeouts in his 37.2 innings. Of course, that means plenty of in-play action as well, with opposing batsmen getting a fair amount of contact.

Freddie Freeman profiles well against Darvish, with Shohei Ohtani always a priority play. After that duo, let personal preference and of course salary constraints guide your selections, with Teoscar Hernandez, Andy Pages and catcher Will Smith the next wave of options. No, Mookie Betts was not inadvertently left out, but skipping over the struggling former MVP is an easy way to create differentiation from other Los Angeles stacks.

To be clear, the boys in blue have a low stack probability on the featured-slate. That makes sense, when considering the upgrades made to the San Diego bullpen and manager Mike Shildt ready to have a quick hook, with every game being crucial for the season standings as the league heads towards the finish line.

Gamers are going to be looking to the Chicago Cubs in Anaheim against LHP Tyler Anderson as the priority late-slate play, while Houston looks good on the road in Baltimore against LHP Cade Povich and the Minnesota Twins face RHP Aaron Civale in Chicago as other featured-slate stacking candidates.

Today’s Top Sports Betting Picks

If you’re serious about making sharp MLB DFS picks, you already know that long-term success starts with using the right information. The same approach applies to sports betting — and that’s where Tails By OddsShopper shines.

Take a bet like Hunter Goodman to hit a home run tonight. On the surface, it’s a simple play. But behind the scenes, it’s a +EV bet, meaning it’s mathematically profitable based on the best odds available. With Tails, you can follow experts who provide tons of other +EV bets just like this. Upgrade to full Tails packages to join expert Discords, or check out the Free Picks page for daily updates.

It is always tricky leaving Coors Field’s altitude and going to a low-elevation park, but the +575 for Goodman to hit a home run tonight is very enticing. He will be facing rookie starter RHP Braxton Ashcraft, who is converting into a starter. The soon-to-be 26-year-old is likely to log 65-to-70 pitches, or around four innings. Ashcraft is a solid prospect, though he still could use some more seasoning, with just over 100 innings at Triple-A or The Show.

Home runs are fickle and it is also VERY IMPORTANT to find “good numbers” before placing a wager. Currently the line is being offered from +450 all the way to the +575 at Bally’s. That is a range of negative 11% to positive 10% expected ROI which is just wild. For someone like Your Ol’ Pal, who is in Florida and limited to only Hard Rock, sitting out with the +450 current offer is the savvy strategy, since there will be many other wagering opportunities, especially with NFL and CFB right around the corner. Be a savvy shopper!


How to get the most out of your MLB DFS picks with Stokastic Sims — it’s more than just an MLB DFS optimizer! Also, check out Stokastic’s best DFS podcasts for more information every day. Click here for the best MLB DFS podcast!

Eric "EMac" MacPherson won the 2007 Fantasy Baseball grand prize (trip for two to the MLB All-Star game) in the Roto format on ESPN. He won again in 2008, this time in the H2H format. As one of the early adopters of daily fantasy sports, EMac has been providing content for baseball and basketball as well as both professional and college football since 2012 for a variety of websites including DraftKings Playbook, FanVice, RotoWorld, Daily Fantasy Bootcamp, and RotoGrinders. He is well into his third decade of fantasy sports and has a wealth of knowledge and experience. Follow him on Twitter @EMacDFS or contact EMac by emailing [email protected].

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