NFL DFS Week 2 DraftKings Picks: Best Stacks, One-Offs, and Leverage from Stokastic’s Sims

With Week 2 on deck, Stokastic’s NFL DFS Sims have already run thousands of DraftKings lineups. Looking at the top 300 outputs gives us a roadmap of where the math is leaning. Instead of just raw percentages, let’s dig into which stacks, one-offs, and leverage plays stand out as the best NFL DFS Week 2 picks.

NFL DFS Week 2 Picks: Best Stacks and Leverage Plays from Stokastic’s Sims

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Quick Slate Snapshot (Exposure Within the Top 300)

• QB: Joe Burrow (39, 13.0%), Patrick Mahomes (37, 12.3%), Dak Prescott (33, 11.0%)
• RB (overall appearances incl. FLEX): Alvin Kamara (164, 54.7%), Christian McCaffrey (137, 45.7%), Kyren Williams (69, 23.0%)
• WR: Puka Nacua (95, 31.7%), Hollywood Brown (107, 35.7%), D.K. Metcalf (75, 25.0%)
• TE: Jake Ferguson (70, 23.3%), Trey McBride (98, 32.7%), Harold Fannin Jr. (47, 15.7%)
• DST: Ravens (103, 34.3%), Saints (51, 17.0%), Dolphins (34, 11.3%)

Best NFL DFS Stacks

Joe Burrow (39 lineups, 13.0%)

• Top pairs: Ja’Marr Chase (31, 10.3%), Tee Higgins (26, 8.7%)
• Top double stack: Chase + Higgins (18, 6.0%)
  Takeaway: Burrow stacks are concentrated with premium WR (Chase) plus a second pass-catcher appears frequently. If you play Burrow, double is the default shape in these Sims.

Patrick Mahomes (37, 12.3%)

• Top pairs: Hollywood Brown (37, 12.3%), Travis Kelce (33, 11.0%)
• Top double stack: Brown + Kelce (33, 11.0%)
  Takeaway: Mahomes lineups overwhelmingly pair Brown + Kelce. If you’re fading Kelce at TE, recognize the sims still love him with Brown in Mahomes builds.

Dak Prescott (33, 11.0%)

• Top pairs: CeeDee Lamb (24, 8.0%), Jake Ferguson (24, 8.0%)
• Top double stack: Lamb + Ferguson (16, 5.3%)
  Takeaway: The Lamb + Ferguson double is the signature Cowboys stack; Ferguson’s TE price relief keeps showing up.

One-Offs the Sims Treat Like Core Plays

These are players repeatedly showing up across many builds independent of a single QB stack.

• Alvin Kamara — 164/300 (54.7%). Massive usage at RB; fits with almost any stack shape.
• Christian McCaffrey — 137 (45.7%). Similar glue role; salary is the only limiter.
• Trey McBride — 98 (32.7%). Shows up as a TE in stacks and as an accessory piece; bankable volume profile.
• Puka Nacua — 95 (31.7%). Universal WR glue; pops inside many stacks and as a bring-back or floating one-off.
• Hollywood Brown — 107 (35.7%) overall and the Mahomes pairing of choice. Even outside Mahomes, he’s used widely.
• Jaxon Smith-Njigba — 64 (21.3%). Frequent across non-Sam Darnold lineups as salary-tier hinge points.
• Jake Ferguson / Dallas Goedert — Ferguson 70 (23.3%), Goedert 63 (21.0%). Both provide structure at TE in premium QB stacks without swallowing WR cap.

Leverage Plays

• George Pickens — 4.0% overall, appears with top QBs at a 3.67% clip inside the set. Spikes matter when you choose him.
• Rome Odunze — 5.3% overall; strong co-occurrence with Caleb Williams stacks (double with D.J. Moore shows up 12 times).

How to Convert This into DraftKings NFL DFS Lineups

1. Pick your stack first:
   • Examples the Sims love:
     • Mahomes + Brown + Kelce
     • Burrow + Chase + Higgins
     • Prescott + Lamb + Ferguson
     • Williams + Moore + Odunze
2. Add a one-off: Kamara/McCaffrey at RB; Nacua/McBride at WR/TE are the most common glue.
3. Decide your leverage: Rotate mid-exposure WRs (Pickens, Odunze, Calvin Ridley, Malik Nabers, Brian Thomas Jr., A.J. Brown) around the core.
4. Close with DST: Default Ravens; pivot to Saints/Dolphins/Rams for duplication control.

This mirrors the shape of the NFL DFS Week 2 picks the Sims are implicitly making and keeps your roster aligned with the highest-probability constructions.