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Top 4 NFL PrizePicks for Week 10 Monday Night Football | 49ers vs. Rams

Geoff Ulrich

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Monday Night Football for Week 10 features an NFC West duel between the struggling San Francisco 49ers and the Los Angeles Rams. The Rams are 3.5-point favorites despite being the visitors. They have had a busy week, as they added Odell Beckham Jr. as a free agent and then promptly lost Robert Woods for the season to an ACL injury. The 49ers are mostly healthy on offense, with both George Kittle and Elijah Mitchell slated to play. On defense they could be without a couple of members of their secondary, opening the field even more for the Rams wideouts. This game has an over/under of 50, and the Rams have a high implied team total of 27.5. We will use the Awesemo DFS projected stats to try and find the best player props to attack on PrizePicks for this game.

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Week 10 Monday Night Football NFL PrizePicks

Matthew Stafford Over 280.5 Yards Passing

For betting purposes, attacking these low Matthew Stafford passing totals has been very profitable in 2021. Stafford has thrown for 280 yards or more in seven of his nine starts, and he has gone for over 290 in six of nine. For whatever reason, the total sits 27 yards below his seasonal average of 307 yards this week. Stafford is also projected to go for over 310 yards in the Awesemo projections.

The 49ers have done well at limiting big plays, and they have allowed just 6.7 yards per pass attempt, which is 14th best in the NFL. Only once has a quarterback thrown for more than 260 yards against them in 2021 (Jared Goff Week 1). Still, the Rams passing attack is likely to win out. They are averaging 8.5 yards per pass attempt and have been productive through the air against every opponent they have faced so far. Take the over on this gift total

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George Kittle Over 55.5 Yards Receiving

Over his last three games Kittle is averaging 9.5 targets and posted his best game of the season his last time out, going for six catches, 101 yards and a touchdown against a tough Arizona defense. When healthy, Kittle is a yards-after-catch monster and has averaged 74.6 yards receiving per game in 27 games since the start of the 2019 season. Even better, Kittle has typically destroyed the Rams and comes into this game having gone for 97 yards per game against them over their last three meetings (where he has been healthy). Kittle is taking back a bigger target share in this offense, but his totals do not reflect that shift yet. Awesemo projects him to go over this smallish total, and he makes for a nice addition to any combo tickets on PrizePicks.


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Jimmy Garoppolo Over 0.5 Interceptions

It is not possible to be bullish on everyone in this game, but gamers can also attack some potential poor play through the turnover props on PrizePicks. Jimmy Garoppolo has thrown an interception in 80% of his regular-season starts over the last three seasons and faces a Rams defense that ranks second in interceptions with 11. The 49ers got down early last week against Arizona and threw 40 times (Garoppolo had one interception), and similar volume could be coming, especially with the 49ers currently set as decent home underdogs. Garoppolo has the seventh-highest chance of throwing an interception of all Week 10 quarterbacks according to Awesemo, and Garoppolo’s interception total makes for a good target for another over.

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